Overview
- Affinity purification of human IgG1, IgG2 and IgG4, rabbit IgGs, FC-fusion proteins and etc.
- Excellent for acid-sensitive and unstable IgGs and FC-fusion proteins.
- Downstream Bioprocessing
- Immunoprecipitation
Elution pH for IgGs | pH 4.5-4.7 |
Dynamic Binding Capacity, 10%QB | Up to 60 mg/mL IgGs at 4 min residence time |
Static Binding Capacity | Up to 70 mg/mL of IgGs |
Alkali-Tolarence, CIP | Stable Up to 50 CIP cycles with 0.5 M NaOH |
Matrix | Highly crosslinked agarose beads |
Bead Diameter | average 70 um |
Ligand | Engineered Protein A ligand (patented) |
Maximal Flow Rate | 300 cm/h |
Buffer Compatibility | All common aqueous buffers |
pH Stability | pH 2 - pH 12 |
Storage | 4-10 ˚C, with 20% isopropanol |